This $161,671 Project Grant award from the National Institute on Aging (CFDA 93.866 - Aging Research) supports an investigation by The Ohio State University into the associations between biological aging and outcomes, neuroimaging findings, and immune dysregulation in multiple sclerosis (MS). The 5-year project aims to establish a geroscience framework for studying the role of aging processes in MS progression and developing interventions to mitigate or prevent disease progression. The research will consist of cross-sectional and longitudinal analyses integrating clinical, neuroimaging, and molecular data to better understand how biological aging impacts MS. This work will lay the foundation for future studies to utilize biological aging as a prognostic biomarker and evaluate anti-aging therapies in combination with MS disease-modifying treatments.
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