This federal Project Grant award from the National Institute on Alcohol Abuse and Alcoholism (NIAAA), under the Alcohol Research Programs (CFDA 93.273) federal grant program, supports a research study aimed at adapting and implementing Screening, Brief Intervention, and Referral to Treatment (SBIRT) for adolescents with chronic medical conditions (A-CMCs) who are hospitalized in pediatric inpatient units. The $150,497 award will fund a single arm hybrid effectiveness-implementation pilot trial to test a set of implementation strategies and the adapted SBIRT intervention. The study objectives include observing inpatient workflows, collaborating with a partner steering committee to adapt SBIRT, and selecting SBIRT implementation strategies for the pediatric inpatient setting and population. The primary recipient is Ann & Robert H. Lurie Children's Hospital of Chicago, a major academic medical center that frequently secures federal research grants and contracts to advance pediatric healthcare. The project period runs from September 2024 through August 2029.