This federal Project Grant award, valued at $168,084.00, was provided by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) under the Diabetes, Digestive, and Kidney Diseases Extramural Research program (CFDA 93.847). The award supports a five-year research and career development program focused on investigating the role of endoplasmic reticulum stress in innate lymphoid cells and their impact on intestinal inflammation, particularly in the context of inflammatory bowel disease. Led by Principal Investigator Dr. Siyan Cao at the Washington University School of Medicine, the research will leverage expertise from multiple mentors and an advisory committee to advance understanding of the cellular stress response pathways that regulate innate immunity in gut inflammation. The findings are expected to open new avenues for biomarkers and novel management approaches for inflammatory bowel disease.