Project Grant CE154199
Award Date
9/30/24
Completion Date
9/29/27
Dollars Obligated
$32M
Funding Federal Agency
Healthcare Systems Bureau
Awarding Federal Agency
Office of Federal Assistance Management
Federal Grant Program
93.493
Assistance Type
Project Grant
Place of Performance
Bar Harbor, ME, USA
Similar Awards
This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) provides $716,587 to Boston Children's Hospital to advance equity in rare disease genomic research. The key objectives are to: Develop and implement a Diversity, Equity, and Inclusion toolkit within the Broad Institute's Rare Genomes Project to improve engagement and participation from historically underrepresented populations in rare disease genomic studies. This will involve...
This Project Grant award from the National Human Genome Research Institute (CFDA 93.172 - Human Genome Research) aims to gain a multi-perspective understanding of the ethical challenges arising in patient-focused drug development (PFDD) for rare diseases and to develop tools to manage these challenges. The $1,276,313 award, effective February 1, 2025 through January 31, 2029, will fund a study with three key objectives: 1) explore stakeholder perspectives on ethical issues in PFDD, 2)...
This $20,000,000 Project Grant award from the U.S. Department of Health and Human Services (HHS) under the Congressional Directives program (CFDA 93.493) will support the continued design and construction of a Current Good Manufacturing Practices (CGMP) capable facility on the University of Delaware's Science, Technology, and Advanced Research (STAR) campus. The envisioned Securing American Biomanufacturing Research and Education (SABRE) Center will provide critical infrastructure to enable...
This $449,000 Project Grant was awarded on September 30, 2024 by the Department of Health and Human Services (CFDA 93.493 - Congressional Directives) to Jackson Laboratory, a non-profit biomedical research institution located in Bar Harbor, Maine. The grant supports the construction or renovation of healthcare facilities, as part of congressionally directed community projects focused on addressing the healthcare needs of underserved populations. Jackson Laboratory has a robust portfolio of...
The Department of Health and Human Services (HHS) awarded a $8,000,000 Project Grant under the Congressional Directives program (CFDA 93.493) to Cold Spring Harbor Laboratory (CSHL), a non-profit research and education institution in New York. The grant funds the construction and renovation of healthcare facilities, equipment purchases, and the delivery of specialized health and social services programs to address specific local and regional needs as directed by Congress. CSHL, which has...
This Project Grant award of $743,926 from the National Institutes of Health (NIH) under the Research Infrastructure Programs (CFDA 93.351) will develop a resource of rigorously validated, translatable zebrafish models of previously undiagnosed human genetic diseases. The project will analyze genetic variants obtained from patients with rare, undiagnosed diseases through collaboration with clinical research consortia, and then generate humanized zebrafish models using CRISPR/Cas9 technology....
This $110,000 Project Grant award from the National Center for Advancing Translational Sciences (NCATS) under CFDA 93.350 supports research by Greenstone Biosciences, Inc. to develop advanced drug discovery and development technologies for rare genetic disorders. The project aims to leverage induced pluripotent stem cell (iPSC) technology and artificial intelligence/machine learning (AI/ML) to accelerate and streamline the drug discovery process for myotonic dystrophy type 1 (DM1), a rare and...
This Project Grant award of $1,819,296.00, issued by the National Institute of Child Health and Human Development (NICHD) under the Child Health and Human Development Extramural Research program (CFDA 93.865), will fund research to unravel the genomic causes for unsolved leukodystrophy patients. The award will utilize long-read genome sequencing (HiFi-GS) to identify complex genetic variants, such as repeat expansions and structural variants, that are often missed by standard short-read genome...
This $20,000,000 Project Grant award from the Healthcare Systems Bureau of the U.S. Department of Health and Human Services under the Congressional Directives program (CFDA 93.493) will support the Regional Medical Center at Lubec, Inc. in constructing a new healthcare facility in East Machias, Maine. The new facility will increase access to both medical and dental services in the underserved Washington County area by adding an additional medical provider, a dentist, and a dental hygienist to...
This Project Grant award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), under the federal Child Health and Human Development Extramural Research program (CFDA 93.865), provides $121,920 to the University of North Carolina at Chapel Hill to investigate the role of the protein RFT1 in growth and developmental signaling. The research aims to elucidate how RFT1 regulates hedgehog signaling and downstream mTOR complex 2 pathways, which are key...