Project Grant 2533984
- The National Science Foundation (NSF) awarded a $300,011 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the Regents of the University of California at Riverside. The grant, titled "Collaborative Research: FDT-BioTech: Digital Twins with Statistical Topological Learning of Periodontal Diseases", aims to develop novel mathematical and statistical methodologies to establish an AI-driven framework for constructing reliable and personalized digital twins...
- The National Science Foundation (NSF) awarded a $1,000,000 Project Grant under the Computer and Information Science and Engineering (CFDA 47.070) federal grant program to The Trustees of the University of Pennsylvania, doing business as Clinical Practices of the University of Pennsylvania. The grant supports the development of an intraoral device that integrates multimodal data from the oral microbiome to predict risk for systemic health issues like neurological problems, heart disease, and...
- This $349,996 federal Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program aims to develop a new dental technology to improve oral health through microbial transplantation. The project will test the use of beneficial oral microbes from healthy donor dental plaque to treat conditions like dental decay and gum disease in recipients. The effort will employ a 3D printed system to grow and propagate the transplanted microbes, with the...
- This National Science Foundation (NSF) Project Grant award under the Mathematical and Physical Sciences program (CFDA 47.049) provides $370,774 to the University of Houston System to develop an innovative framework for learning digital twins of human physiology. The goal is to create personalized, data-enabled digital models that can simulate glucose metabolism and help evaluate new treatments and technologies for type 1 diabetes management, without the risks of real-world trials. The research...
- This Project Grant award, valued at $175,007, was provided by the National Science Foundation (NSF) under the Computer and Information Science and Engineering (CISE) Federal Grant Program (CFDA 47.070). The award supports the development of a new framework for digital twin modeling of Alzheimer's disease (AD), combining clinical data, biomedical research, and advanced computational methods to enable personalized medicine. The project aims to build a unified modeling framework for...
- This $499,996 federal Project Grant award from the National Science Foundation's Biological Sciences Program (CFDA 47.074) will fund a research project conducted by The Pennsylvania State University to reconstruct the history of the human oral microbiome on a global scale. The project aims to understand the evolutionary mechanisms that drive changes in human microbiome diversity over time, particularly in response to shifts in geography, environment, and culture. By analyzing bacteria...
- This Project Grant award from the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program provides $201,974 to Loyola University of Chicago to investigate the progression of dental wear and dental senescence over a 50-year simulated chewing period. The study employs a custom chewing simulator to measure changes in dental function, occlusal topography, microstructure, and elemental composition of extracted third molars. This research aims to advance the...
- This Project Grant from the National Science Foundation's Engineering program (CFDA 47.041) provides $249,999 to The Trustees of the University of Pennsylvania for the development of a smart dental implant system. The award will support research and educational activities from September 2022 through August 2025. Specifically, the grantee will build a strategy to prevent peri-implant disease through enhancing soft tissue immunity near dental implants. They will develop an ambulatory care platform...
- This Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program aims to improve diabetes care through the development of personalized digital twin models. The $716,195 award to the Research Foundation for the State University of New York (RF SUNY) will fund the creation of virtual patient models that can learn from wearable health sensors and guide real-time insulin delivery using automated medical devices....
- This $888,680 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) will support collaborative research by the University of Maryland Baltimore County (UMBC) on developing digital twin models and data science techniques for studying neurodegenerative diseases like Alzheimer's, Parkinson's, and multiple sclerosis. The 3-year project aims to advance the theoretical foundations, methodological tools, and algorithmic principles of...
This $450,892 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) supports the development of novel mathematical and statistical methodologies to establish a foundation for constructing reliable and personalized digital twins for periodontal health. The project aims to integrate principles from statistical learning, topological data analysis, and generative AI to build ensembles of individualized "periodontal digital siblings" that capture patient variability and uncertainty, offering more precise representation of individual health profiles. This interdisciplinary effort bridges mathematics, statistics, machine learning, dental science, and healthcare, with the goal of transforming the prevention and treatment of periodontal disease through personalized, data-driven care. The award is being provided to Virginia Polytechnic Institute & State University, with a project period running from September 15, 2025 through August 31, 2028.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $450.9k | 8/20/25 |