Project Grant 2514598
- This National Science Foundation (NSF) Project Grant, under the Biological Sciences program (CFDA 47.074), provides $240,000 in funding from February 1, 2024 to January 31, 2027 to support a postdoctoral research fellowship focused on investigating a novel circadian time-keeping mechanism revealed by environmental manipulation. The research plan aims to identify the location in the brain and the mechanism of a non-canonical clock that can rescue daily rhythms in mice with disrupted central clock...
- This $380,089.00 federal Project Grant award from the National Institute of General Medical Sciences (NIGMS), under the Biomedical Research and Research Training program (CFDA 93.859), supports fundamental research on the molecular mechanisms underlying circadian rhythms. The project aims to determine the mechanisms that define the period and light-dependent phase shift of circadian rhythms, which are critical for aligning cellular and physiological processes with external environments. By...
- This $850,000 Project Grant award, funded jointly by the National Science Foundation's (NSF) Division of Integrative Organismal Systems and Division of Information and Intelligent Systems under CFDA 47.070 Computer and Information Science and Engineering, supports research to understand how sleep and memory are connected in the brain. The project will use long-duration, high-resolution recordings of neuronal activity to observe changes in synaptic connections during sleep and memory tasks,...
- This federal Project Grant award of $837,277, provided by the National Institute of General Medical Sciences (NIGMS) under the Biomedical Research and Research Training program (CFDA 93.859), supports research at Vanderbilt University to elucidate the fundamental cellular and molecular mechanisms of circadian entrainment and plasticity. The research aims to advance the understanding of how gene networks give rise to physiology, function, and behavior, with a focus on the brain's endogenous...
- The National Science Foundation awarded a $464,102 Project Grant to the New Jersey Institute of Technology under the Mathematical and Physical Sciences federal grant program (CFDA 47.049). The grant will support research merging deep learning and mechanistic modeling to analyze electrophysiology related to circadian clocks, aging, cardiac arrhythmias, and Alzheimer's disease. Specifically, the grantee and collaborators at IBM Research and Purdue University will develop hybrid deep learning and...
- This National Science Foundation Project Grant of $255,851 awarded on September 15, 2022 will support the development of a neuromodulation device to promote healthy sleep cycles through the completion of prototype engineering. The awardee, Neurolight Inc. of Suffern, New York, will utilize controlled light and sound stimuli delivered via an externally worn system to transpose normal brain wave patterns associated with desired sleep states into recipients suffering from sleep disorders. This aims...
- This $399,996 Project Grant awarded by the National Science Foundation's Biological Sciences (CFDA 47.074) program will support research at Saint Joseph's University to explore the mechanisms underlying stress responses and sleep regulation in the model organism Caenorhabditis elegans. The project aims to characterize new neural circuit mechanisms that control avoidance behaviors and recovery sleep in response to threats. The research will be conducted primarily by undergraduate and...
- The National Institute of Neurological Disorders and Stroke (NINDS) awarded a $443,736 Project Grant under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) to The Washington University in St. Louis, Missouri. The grant, which runs from July 1, 2025 to June 30, 2030, supports research to understand how the biological circadian clock generates time markers to align physiology and behavior with the 24-hour day. The research focuses on the...
- The federal Project Grant award R21NS136974 was provided by the National Institute of Neurological Disorders and Stroke (NINDS) under the Extramural Research Programs in the Neurosciences and Neurological Disorders (CFDA 93.853) program. The $466,125 award to President and Fellows of Harvard College, doing business as Harvard Medical School, aims to analyze the composition of two BMAL1 circadian clock complexes purified from the mammalian brain and develop procedures for determining their...
- The National Science Foundation (NSF) awarded a $125,000 Project Grant under its Biological Sciences program (CFDA 47.074) to The General Hospital Corporation, doing business as Massachusetts General Hospital (MGH), for a collaborative research project titled "EAGER: Deep Learning-Based Multimodal Analysis of Sleep." The two-year project aims to develop a multimodal machine learning approach to simultaneously monitor and process electroencephalogram (EEG) data and animal behavior...
The National Science Foundation (NSF) awarded a $7,394,696 Project Grant under the STEM Education (CFDA 47.076) program to the Morehouse School of Medicine, Inc. (MSM) to establish a world-class research center for studying circadian rhythms and sleep. The 5-year project, titled "CREST PHASE I: CENTER FOR CIRCADIAN RHYTHMICITY AND SLEEP HOMEOSTASIS", aims to investigate how circadian disruptions affect the body, focusing on identifying the neuronal mechanisms responsible for circadian clock synchronization and the neurocircuitry underlying sleep. The research will leverage advanced methods including spatial transcriptomics, proteomics, computational neurobiology, and in vivo brain imaging. The expected outcomes are the identification of cellular and molecular mechanisms behind circadian disruptions, which will be disseminated through scientific meetings and publications to benefit the scientific community and the public.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $7.4m | 8/1/25 |