The National Science Foundation (NSF) awarded a $329,206 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program to the University of Utah to support an integrated university-industry research program on developing new methods for hydrogen isotope labeling of pharmaceuticals. The key objectives are to: (1) establish improved chemical methods for labeling pharmaceuticals and their precursors with multiple hydrogen isotope atoms or selective labeling at specific sites using heterogeneous photocatalysis and electrochemistry, and (2) provide learning and training experiences for graduate and undergraduate students in this interdisciplinary field. The three-year project, led by Dr. Long Luo of Wayne State University and Dr. Jingwei Li of Merck & Co., aims to advance the state-of-the-art in hydrogen isotope exchange strategies for isotope labeling, which can enhance drug detection and quantification in preclinical and clinical studies. No subawards are planned under this grant.
Generated 3/18/25, 2:04 AM