The National Science Foundation (NSF) awarded a $129,999.00 Project Grant under the Computer and Information Science and Engineering (CFDA 47.070) federal grant program to Texas State University. This 5-year grant, effective January 1, 2025, supports the development of SPEED, a scalable and efficient modeling framework that captures relationships between application configurations and performance on high-performance computing (HPC) systems. SPEED leverages generative artificial intelligence to enable automated, real-time decision-making for optimizing the performance of dynamic HPC applications. The project outcomes can be applied to high-impact domains like disaster response, healthcare, and manufacturing to accelerate data-driven decision-making. Additionally, the grant will equip students with advanced skills in HPC and AI, contributing to the national scientific workforce. Texas State University, a Hispanic-serving institution, has a track record of delivering technical services and research through federal prime and sub-awards across disciplines.