The University of Utah's Office of Sponsored Projects Division has been awarded a $543,251 Project Grant from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. This 3-year grant, effective from September 1, 2024 to August 31, 2027, supports the development of chemically tunable models of the cellular glycocalyx, a protein and sugar coating on cell surfaces. The research aims to systematically investigate the role of mucin glycoproteins in regulating cellular signaling and epithelial homeostasis. The project will enable graduate and undergraduate students to gain specialized training in sugar and protein chemistry, as well as cell biology, while also supporting K-12 outreach on the building blocks of life. The ultimate objective is to develop tools for studying the glycocalyx and contribute to the fundamental understanding of its biochemical and biophysical functions.
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