This National Science Foundation (NSF) Project Grant award under the Engineering (CFDA 47.041) program totaling $165,437 is funding research to visualize and characterize the motion and interaction of individual nanoparticles near surfaces. The awardee, Georgia Tech Research Corporation, will develop a workflow combining nanoscale microscopy with data-driven modeling to study how nanoparticles move and interact in heterogeneous environments, with applications in areas such as nanomedicine,...
The National Science Foundation Division of Materials Research awarded a $438,521 project grant to the Georgia Tech Research Corporation from July 1, 2021 to June 30, 2024. The grant supports research titled "Engineering Responsive Chemical Heterogeneity in Protein Vesicles for Simultaneous Delivery of Diverse Cargoes" under the Mathematical and Physical Sciences program (CFDA 47.049). The research aims to develop protein vesicle delivery systems that can encapsulate and release...
This $578,955 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program supports research to create "metabolic" droplets where chemical activity alters and controls material properties. The principal investigator at The Trustees of Columbia University in the City of New York aims to couple enzymatic activity to phase separation in vitro, with the goal of animating equilibrium materials to capture life-like properties....
This Project Grant award from the National Science Foundation's Engineering program (CFDA 47.041) will provide $200,000 to the Trustees of the Stevens Institute of Technology to investigate the behavior of molecules confined in small porous structures. The project aims to synthesize polymeric nanospheres containing gold nanoparticle templates, which will then be removed to create porous structures. By adjusting the geometry and distribution of these pores, the project will explore how the...
This Project Grant award of $420,887, provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), supports the development of a multi-enzyme immobilization system in metal-organic materials for rapid and sustainable degradation of plant biomass. The key products and services to be delivered under this award include: Developing a "5-in-1/Ca-BDC biocatalyst" that simultaneously immobilizes five enzymes (three cellulases, a lipase, and a...
The National Science Foundation (NSF) awarded a $405,960 Project Grant to Rensselaer Polytechnic Institute (RPI) under the Mathematical and Physical Sciences program (CFDA 47.049) to investigate enzymes from organisms living in deep sea environments. The research aims to understand how these enzymes, known as extracellular deoxyribonucleases (exDNases), have adapted to function under the extreme conditions of high pressure and temperature in the deep ocean biosphere. The work will combine...
The National Science Foundation (NSF) awarded a $200,000 Project Grant under the Engineering program (CFDA 47.041) to the Trustees of the Stevens Institute of Technology in Hoboken, NJ. The award will fund research to characterize the nanoscale interactions between biomass-derived carboxylic acids and a platinum catalyst in aqueous reforming processes. This work aims to provide insights on how to design deactivation-resistant catalysts for converting biomass waste streams into renewable hydrogen...
This $220,000 Project Grant award from the National Science Foundation's (NSF) Engineering program (CFDA 47.041) aims to advance the understanding of how soft, deformable particles, such as oil droplets and cells, move through complex environments consisting of narrow constrictions and obstacles. The award to Emory University will systematically investigate the flow of bubbles and droplets through obstacle arrays, studying the effects of particle surface tension, obstacle density, size, and...
The National Science Foundation Division of Materials Research awarded a $250,000 Project Grant to Georgia Tech Research Corporation to support research under the Mathematical and Physical Sciences federal grant program (CFDA 47.049) from September 1, 2023 through August 31, 2026. The award will fund the development of novel classes of organized nanoscale biomolecular materials for controlled molecular transport. Specifically, the grantee will synthesize and study biomolecular magnetic organic...
This Project Grant award, totaling $150,000.00, was provided by the National Science Foundation's (NSF) Engineering program (CFDA 47.041) to Claremont McKenna College. The award supports a collaborative research project aimed at discovering enzymatic pathways to break carbon-fluorine bonds in perfluorinated carboxylic acids (PFAS), which are costly to remove from the environment. The project will engineer special enzymes capable of degrading these stable chemical bonds, with the goal of...
This National Science Foundation (CFDA 47.049 - Mathematical and Physical Sciences) Project Grant award of $503,611 to the Georgia Tech Research Corporation will fund research to develop switchable, hydrophobic enzyme vesicles that can simultaneously enable high-reactivity enzymatic processes and product separation. The research aims to create a design space for engineering enzyme vesicles that can effectively convert hydrophobic substrates in aqueous environments and capture the resulting products, eliminating the need for traditional two-phase solvent-aqueous processes and improving the sustainability of industrial biocatalysis. The research will focus on a dehalogenase enzyme that can be used for both organic synthesis and environmental remediation of pollutants. In addition to the technical research, the project will provide hands-on experiments, mentoring, and professional development opportunities for middle and high school students to promote STEM engagement. This award runs from November 1, 2025 to October 31, 2027.