The National Science Foundation (NSF) awarded a $516,308 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to Virginia Polytechnic Institute & State University, doing business as Virginia Tech, for research on enantioselective syntheses of organoboron compounds via transition-metal catalysis. The principal investigator, Dr. Ming Chen of Auburn University, is developing new methods to prepare chiral, non-racemic organoboron compounds that can serve as versatile building blocks for organic synthesis, materials science, and medicinal chemistry applications. The research team is investigating cobalt-catalyzed hydroboration reactions to access enantioenriched 1,1-bisborylalkanes, which will enable the synthesis of complex organoboron structures not feasible through current techniques. This work provides valuable research training opportunities for graduate and undergraduate students. The award has an effective date of May 15, 2024 and an ultimate completion date of March 31, 2027.
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