This Project Grant award of $249,668 was provided by the National Science Foundation (NSF) Division of Chemistry's Broadening Participation Program under the Mathematical and Physical Sciences (MPS) Federal Grant Program (CFDA 47.049). The award supports Professor Blakely Tresca and students at Kalamazoo College in developing self-assembled diyne peptoid nanomaterials for sensing applications. The key products and services to be delivered include:
Synthesizing 1,3-diyne peptoids and characterizing their reactivity in self-assembled nanosheets. Developing methods to produce diyne precursors on a gram scale and prepare diyne peptoids using automated synthesis. Initiating topochemical polymerization of diyne peptoid nanosheets using heat and UV light. Measuring the reactivity of diyne nanosheets and properties of resulting materials through various spectroscopy and microscopy techniques. Studying small molecule models to understand solid-state packing and monomer reactivity using X-ray crystallography and NMR. This research aims to describe rational design rules for diyne monomer structures and polymer sequences to develop stable nanomaterials as integrated sensors. The award period runs from September 1, 2024 to August 31, 2026.
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