Project Grant 2414429

Award Date 8/1/24
Completion Date 7/31/27
Dollars Obligated $500K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Santa Barbara, CA 93106, USA
Similar Awards
This $575,000 Project Grant award from the National Science Foundation's Mathematical and Physical Sciences (CFDA 47.049) program to the University of California, Berkeley will support Professor Thomas Maimone's research on developing new synthetic strategies for constructing complex, nitrogen-containing molecules. The work aims to identify transformations that can efficiently produce unique target molecules with potential applications in pharmaceuticals, agrochemicals, and materials. The...
The University of California Irvine will assess the applicability of Marcus theory to excited-state proton transfer and protonic photo-chemical energy conversion under a $349,768 Project Grant from the National Science Foundation Division of Chemistry. The grant was awarded on July 1, 2021 for a three-year period concluding on June 30, 2024. The research supports the Mathematical and Physical Sciences program's goals of advancing scientific knowledge and understanding of major problems in...
This Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), provides $470,150 to Professor Linda Shimizu of the University of South Carolina from August 1, 2022 to July 31, 2025. The funding supports research to precisely engineer self-assembling nanotube structures from 3 to 150 monomers of bis-urea macrocycles for applications in photochemistry, molecular electronics, and photodynamic therapy. Specific...
The Regents of the University of California, doing business as the University of California, Berkeley, received a $750,000 Project Grant award from the National Science Foundation Division of Chemistry on September 1, 2022 to complete work by August 31, 2025. The grant funds research led by Professor Ke Xu at UC Berkeley to develop ultrahigh-throughput approaches for single-molecule spectroscopy and multidimensional super-resolution microscopy. Specifically, the team aims to expand the...
This $575,000 Project Grant from the National Science Foundation's Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), will fund research at the University of California, San Diego to synthesize and study the reactivity of unusual main group elements stabilized by transition metal isocyanide complexes, from July 1, 2023 to June 30, 2026. Specifically, Professor Joshua S. Figueroa will manipulate boron monofluoride and diphosphorus molecules, which are...
This Project Grant award of $139,543, provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences (CFDA 47.049) program, supports the development of Extended Lifetime Peroxynitrite-Responsive Probes (XL-PRPs) at the University of California, Santa Barbara (UCSB). The XL-PRPs are a novel class of biomaterials designed for long-term, non-invasive monitoring of peroxynitrite, a biomarker closely linked to the severity of chronic diseases. The project aims to achieve...
This Project Grant award, provided by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049), will support Professor Trevor Hayton of the University of California, Santa Barbara (UCSB) in the development of triphenylmethyl (trityl) group-based small molecule delivery agents, magnetic materials, and metal nanoclusters. The $580,406 award over 3 years (9/1/2024 - 8/31/2027) will enable Professor Hayton to explore new synthetic methodologies,...
The University of California Irvine received a $475,000 project grant award from the National Science Foundation to support research activities under the agency's Mathematical and Physical Sciences program from April 1, 2021 through March 31, 2024. The grant funds the "Innovating New Strategies for Selective Electrocatalytic Reduction" project, which aims to advance understanding of major problems in catalysis science through development of new approaches for selective electrocatalytic...
The National Science Foundation (NSF) awarded a $703,319 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Maryland, College Park. The grant supports the development of novel mass spectrometry-based techniques to characterize the dynamic mitochondrial activities and interactions at the molecular level in human, stem cell-derived neurons. The project aims to address major technical challenges and knowledge gaps in studying the subcellular...
The National Science Foundation Division of Chemistry awarded a $537,452 Project Grant to the University of Arizona under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new light-promoted chemical reactions for studying the biological role of the mitochondrial translocator protein tryptophan-rich sensory protein (TSPO). Over a three-year period from November 1, 2022 to December 31, 2025, Dr. Michael Taylor will design photoactivatable probes and conjugation reactions...

This $500,000 Project Grant award from the National Science Foundation's (NSF) Mathematical and Physical Sciences program supports Professor Justin Wilson of the University of California, Santa Barbara in developing new small-molecule inhibitors of the mitochondrial calcium uniporter (MCU) and investigating their mechanisms of action. The key objectives are to synthesize releasable MCU inhibitor analogues with tunable activation properties, develop externally-triggered releasable MCU inhibitors, and evaluate the new MCU inhibitor tools in cellular models, particularly related to ischemia-reperfusion injury. This research aims to provide a better understanding of the role of mitochondrial calcium uptake in biological processes and human disease. In addition, the award will fund the development of a new educational game to introduce middle and high school students to the diversity of chemists and encourage greater participation in STEM fields. The project period runs from August 1, 2024 to July 31, 2027.

Generated 5/13/25, 4:05 AM