Project Grant 2400070

Award Date 5/1/24
Completion Date 4/30/27
Dollars Obligated $595K
Awarding Federal Agency
Division of Chemistry
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Bozeman, MT 59717, USA
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  1. Developing a model to predict the influence of factors like palladium coordination, ligand properties, and solvent on the mechanism of oxidative addition reactions.
  2. Investigating how the nucleophilic coupling partner impacts the oxidative addition step.
  3. Developing new palladium(0) catalyst precursors.

This research aims to provide a better fundamental understanding of the oxidative addition process in palladium-catalyzed cross-coupling reactions, enabling more efficient and selective organic synthesis methods. The project also includes an educational component focused on visualizing organic reaction mechanisms and providing students hands-on training in molecular modeling.

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