The National Science Foundation (NSF) awarded a $737,423 Project Grant to Purdue University through its Mathematical and Physical Sciences program (CFDA 47.049) to develop a novel dual-comb fluorescence-detected photothermal mid-infrared (DC-FPTIR) microscope. This instrument enables high-resolution optical microscopy with contrast from specific molecular bonds, facilitating research in nanoparticle and advanced materials analysis, biological systems, and measurement of molecular composition in plants and animals. The award supports the fundamental science research of Professor Garth Simpson and colleagues, as well as enhancing educational, research, and training activities at all levels across multiple departments at Purdue. The developed instrument will also benefit the NSF-supported Center for Bioanalytic Metrology and outreach efforts of the Young Institute for Advanced Manufacturing of Pharmaceuticals. The grant period runs from September 1, 2023 through August 31, 2026.
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