Project Grant 2302483
- This five-year Project Grant from the National Science Foundation's Mathematical and Physical Sciences program provides $558,660 in funding to the University of Arizona from February 1, 2022 through January 31, 2027. The grant supports research into red-light mediated photoredox catalysis by helical carbenium ions, with the goal of advancing understanding of major problems in chemistry. As the prime awardee, the University of Arizona will conduct the proposed research and deliver related...
- Professor Kutateladze of the University of Denver will use a $575,000 National Science Foundation Project Grant from the Mathematical and Physical Sciences program (CFDA 47.049) to further develop photoassisted approaches for the synthesis of complex heterocyclic molecules with potentially useful therapeutic properties. Over a three-year period from September 2023 through August 2026, his research aims to expand the synthetic photochemistry toolbox, specifically excited state intramolecular...
- The University of Texas at Austin was awarded a three-year, $450,000 Project Grant from the National Science Foundation under the Mathematical and Physical Sciences program (CFDA 47.049). The grant will support research into boron dipyrromethane photocages for mild and selective light-driven polymer chemistry from September 2021 through August 2024. The funding will enable the development of photolabile protecting groups to enable light-triggered reactions for polymer synthesis and modification,...
- The National Science Foundation (NSF) awarded a $575,000 project grant under its Mathematical and Physical Sciences (MPS) program to the University of Wisconsin-Madison to study the use of light in organic synthesis. Under this 3-year award effective July 1, 2024, Professor Tehshik Yoon and his team will design novel photocatalysts that can interact directly with small molecules to control how they react and form more complex products. The research aims to transform discovery in pharmaceutical...
- This Project Grant award of $510,759 from the National Science Foundation (NSF) Division of Chemistry supports a research collaboration led by Professors Andrew Mitchell of Illinois State University and Dean Tantillo of UC-Davis. The goal is to develop new chemical reactions with connections to biology, medicine, physics, materials, and environmental sustainability. Key products include: Advancing oxidopyrylium-based [5+2] cycloaddition reactions to construct important heterocyclic small...
- The University of Arizona was awarded a $475,000 Project Grant from the National Science Foundation Division of Chemistry to support the development of stable carbocations for Lewis acid-assisted transformations from August 1, 2021 to July 31, 2024. This award falls under the Mathematical and Physical Sciences program (CFDA 47.049), which aims to promote progress in these scientific fields and strengthen the national scientific enterprise through increasing knowledge and enhancing...
- This Project Grant award of $555,000 from the National Science Foundation's (NSF) Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports research by Professor James Allen and Dr. Joann Williams of Arizona State University to study how proteins control proton-coupled electron transfer reactions. The researchers aim to create reversible, long-lived electron and proton transfer processes that mimic biological systems. By manipulating bacterial reaction...
- The U.S. National Science Foundation (NSF) awarded a $426,000 project grant under the Mathematical and Physical Sciences (CFDA 47.049) program to The Regents of the University of California, San Francisco (UCSF) to conduct collaborative research on developing novel protein-based materials for photosynthetic energy transduction. The multi-year project, led by Professors Michael Therien and David Beratan of Duke University and William DeGrado of UCSF, aims to design and construct protein-based...
- The National Science Foundation Division of Chemistry awarded the University of Texas at Dallas a $450,000 Project Grant under the Mathematical and Physical Sciences program (CFDA 47.049) to develop smart photochromic electronic devices. Professor Michael C. Biewer and students will synthesize novel light-activated organic semiconducting materials incorporating a bicyclic aziridine photochromic unit. They will attach this unit as a pendant group to donor-acceptor-donor small molecules based on...
- The National Science Foundation (NSF) awarded a $740,797 Project Grant under the Biological Sciences federal grant program (CFDA 47.074) to the Regents of the University of California, San Francisco (UCSF) to develop and test new methodologies for the rational design of minimalistic light-switchable single-domain proteins. The goal is to engineer these proteins to bind specifically to target proteins in only one photoswitchable chromophore state, allowing for precise spatial and temporal control...
The National Science Foundation Division of Chemistry awarded a $537,452 Project Grant to the University of Arizona under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new light-promoted chemical reactions for studying the biological role of the mitochondrial translocator protein tryptophan-rich sensory protein (TSPO). Over a three-year period from November 1, 2022 to December 31, 2025, Dr. Michael Taylor will design photoactivatable probes and conjugation reactions enabling iterative protein labeling sequences controlled through light activation. This work aims to generate new insights into TSPO's biological function through mapping its interactions with neighboring proteins in cellular environments. The grant also supports educational outreach activities promoting STEM enthusiasm among middle school students and Girl Scouts in Wyoming through interactive curricula and demonstrations utilizing the photochemical systems developed under this research.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $537.5k | 10/21/22 |