Project Grant 2234619

Award Date 8/1/23
Completion Date 7/31/26
Dollars Obligated $550K
Federal Grant Program
47.084
Assistance Type
Project Grant
Place of Performance
Stillwater, OK 74078, USA
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This Project Grant award from the National Science Foundation (NSF) under the Partnerships for Innovation - Research Partnerships (PFI-RP) program supports the development of a virtual human testing platform for inhaler innovation and drug delivery optimization.

The $549,999 project, awarded on August 1, 2023 and running through July 31, 2026, aims to create an AI-assisted virtual platform that can accurately simulate airflow, aerosolized medication delivery, and drug translocation in both healthy and diseased lungs. This platform is expected to reduce the time and cost of inhaler development and evaluation by approximately 90% and 66% respectively, accelerating innovations in inhalation device design for pharmaceutical companies. A key component is the integration of disease-specific lung geometries, including for chronic obstructive pulmonary disease (COPD), to help understand how inhalers can deliver accurate therapeutic doses.

The project involves a collaboration between Oklahoma State University, the prime awardee, and Quench Medical Inc., a sub-awardee providing expertise in pulmonary drug delivery technologies. Quench Medical will assist with beta testing the user interface and provide feedback to optimize the virtual human testing platform for commercial use.

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