Project Grant 2212947
- This Project Grant award from the National Science Foundation (NSF) Technology, Innovation, and Partnerships (TIP) program (CFDA 47.084) will develop a novel membrane separation technology to address the energy-efficient separation of small molecules from industrial process streams for a range of industries. The $275,000 award to Avanpore LLC, a for-profit limited liability company located in Woburn, MA, will run from October 1, 2024 to March 31, 2025. The project aims to create functionalized...
- This Cooperative Agreement award, funded by the National Science Foundation (NSF) under the Technology, Innovation, and Partnerships (CFDA 47.084) program, aims to develop a bioprocessing system to isolate and purify therapeutic antibodies directly from cell culture. The $999,998 award to Athem LLC, a minority-owned small business, will enable scaling up a novel nanoparticle-based purification media and an automated prototype system. The goal is to simplify the manufacturing of biologics, reduce...
- This $902,504 cooperative agreement from the National Science Foundation Division of Industrial Innovation under the Engineering program (CFDA 47.041) supports the development of a scalable downstream purification process for gene therapy vectors by Isolere Bio, Inc. of Durham, North Carolina. The non-chromatographic method seeks to address current inefficiencies that lead to single digit yields by utilizing a polypeptide-based reagent combining affinity capture with phase separation and...
- This Project Grant award from the National Science Foundation (CFDA 47.084 - NSF Technology, Innovation, and Partnerships) provides $275,000 to Carrtech Corp, a woman-owned small business manufacturer, to develop an integrated, single-needle filter system to remove glass shards from injectable fluids. The project aims to create a novel, disposable, inline mechanical filter that addresses the current multi-step process healthcare providers must use to filter glass ampoules prior to injection,...
- This National Science Foundation Project Grant of $255,927 awarded to Invvax, Inc. on March 1, 2022 seeks to develop stable prophylactic antibodies through February 2023. Funded through the NSF Engineering Directorate's CFDA 47.041 program, this Small Business Innovation Research Phase I project will engineer mutations to antibody Fc regions to resist degradation and enhance binding to the neonatal Fc receptor for potentially decades-long duration. Specifically, the awardee will combine known...
- This National Science Foundation Project Grant of $477,562 provides funding from August 15, 2022 through July 31, 2025 to develop new predictive mathematical models for membrane filtration. The award is made under the Mathematical and Physical Sciences program (CFDA 47.049) to further the goals of strengthening the Nation's scientific enterprise and increasing scientific knowledge. The awardee, New Jersey Institute of Technology, will work with industrial collaborators and students to derive...
- Award Summary Membranex, LLC, received a Cooperative Agreement from the National Science Foundation (NSF) Technology, Innovation, and Partnerships program (CFDA 47.084) in the amount of $1.25 million, effective July 1, 2025, through June 30, 2027. The project focuses on developing and demonstrating electrospray-based 3D printed membranes designed to enable the reuse of cooling tower blowdown water (CTBW) in industrial applications. The primary deliverable is the design, manufacture, and...
- This National Science Foundation (NSF) Technology, Innovation, and Partnerships (CFDA 47.084) Project Grant award for $275,000 will support the development of a plasmonic nanopore sensor device for quality control of adeno-associated viruses (AAVs) used in gene therapy. The proposed device will enable accurate characterization of AAV payload (single-stranded DNA, double-stranded DNA, or empty) at low, pre-scale-up concentrations to optimize formulations. The project aims to demonstrate the...
- This Project Grant from the National Science Foundation will support the development of a novel hollow-fiber membrane technology tailored for use in a liquid desiccant air conditioning system. Awarded on May 15, 2023 for $255,965 under the NSF Technology, Innovation, and Partnerships program, the grant aims to demonstrate a customized membrane design and quantify its impact on the proposed system's efficiency, size, and cost. The recipient, Zephyr Innovations Inc., plans to conduct a series of...
- This $386,034 National Science Foundation project grant supports the development of chemically resilient, fouling resistant polymer membranes for water separation applications. Funded under the Engineering program (CFDA 47.041), the 24-month award to the University of Massachusetts Amherst enables fundamental research to manufacture porous polymer membranes using an all-aqueous process that eliminates toxic solvents currently used. The research aims to (1) develop a mechanistic understanding...
This $255,982 National Science Foundation project grant supports the development of sustainable, cost-effective viral clearance membranes by Filtravate, Inc. to enable efficient monoclonal antibody processing. The NSF Technology, Innovation, and Partnerships program seeks technologies leading to breakthrough solutions for national challenges. Specifically, Filtravate will develop a virus filtration membrane using a synthesis process that is more sustainable and affordable than conventional methods. The novel membrane aims to address fouling issues that hinder full realization of continuous bioprocessing efficiencies. By producing membranes with narrower pore size distribution and stronger fouling resistance without post-production processes, the technology could enable biomanufacturers to adopt more efficient continuous production methods. This has the potential to lower facility footprints, investment costs, and processing costs for pharmaceutical manufacturers.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $256.0k | 9/6/22 |