Project Grant 2210640

Award Date 8/1/22
Completion Date 7/31/25
Dollars Obligated $200K
Federal Grant Program
47.049
Assistance Type
Project Grant
Place of Performance
Irvine, CA 92697, USA

This three-year $200,000 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports research at the University of California, Irvine to develop new statistical methods and computational tools for analyzing complex, intensive longitudinal biomedical data. Specifically, the grantee will study heterogeneous epigenetic effects of post-traumatic stress disorder using high-dimensional DNA methylation modeling. They will also develop optimal individualized treatment rules incorporating interaction effects for mobile health-monitored conditions like diabetes. A third topic involves using a double encoders approach to estimate omnichannel treatment regimes. The software and models generated will be disseminated for use by industry and health partners. The award reflects the Foundation's mission to advance mathematical and physical sciences and strengthen the national research enterprise.

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