Project Grant 2210316
- This Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA program "Research Related to Deafness and Communication Disorders" (93.173), provides $693,856 to The Regents of the University of California, San Francisco (UCSF) to conduct research on the structure and function of coordinated neural activity in the auditory system. The key objectives of this 5-year research project are to: 1) Identify coordinated neural...
- This Project Grant award of $1,999,999.00, funded by the National Science Foundation's (NSF) Engineering program (CFDA 47.041), supports research inspired by auditory perception in the human brain. The project aims to develop mathematical models to describe neural computations underlying the brain's remarkable ability to focus attention and enhance specific auditory signals while suppressing surrounding noise - a phenomenon known as the Cocktail Party Problem. The research involves engineering...
- This federal Project Grant award from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the CFDA Program 93.173 "Research Related to Deafness and Communication Disorders", provides $690,773 to The Leland Stanford Junior University (Stanford University) from December 15, 2024 to November 30, 2029. The project aims to understand how the hair bundle structure and stimulation in the inner ear shape the receptor current that generates the electrical...
- The University of Iowa was awarded a $750,000 Project Grant from the National Science Foundation to conduct research measuring and mathematically modeling ionic transport in auditory systems from April 1, 2021 to March 31, 2024. The grant was awarded under the National Science Foundation's Biological Sciences program (CFDA 47.074), which aims to promote progress in the biological sciences and strengthen the nation's scientific enterprise through increasing scientific knowledge and enhancing...
- This $401,918 federal Project Grant award from the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences (CFDA 47.075) program supports research by the University of Rochester to investigate neural mechanisms underlying how the brain processes complex sounds like speech and music across different timescales. The key objectives are to use computational models and neural recordings from auditory cortex to understand the brain's flexible integration of sound information over...
- Georgia Tech Research Corporation will receive $348,286 under a three-year Project Grant from the National Science Foundation's Engineering Directorate (CFDA 47.041) to conduct fundamental research on the generation of spontaneous otoacoustic emissions by the inner ear. The research aims to advance understanding of the biophysical mechanisms by which the ear generates sounds in the absence of external stimuli. The project will develop and evaluate computational models of two prevailing...
- This Project Grant award of $500,000.00 from the National Science Foundation's (NSF) Biological Sciences (CFDA 47.074) program aims to advance scientific understanding of hearing in noisy environments. The research team at The Johns Hopkins University, a leading federal contractor and grantee, will conduct an interdisciplinary study to identify the neural mechanisms that confer hearing protection in some species and susceptibility in others. The project includes an educational component to...
- The Regents of the University of California, San Francisco (UCSF) was awarded a $750,000 Project Grant from the National Science Foundation's (NSF) Social, Behavioral, and Economic Sciences program (CFDA 47.075) to conduct collaborative research on individual variability in auditory learning. The research aims to develop a non-invasive device that integrates attention and neuromodulation to enhance second language acquisition, particularly for underserved communities. The multi-modal,...
- This $115,158 Project Grant, awarded on February 1, 2025 by the National Institute on Deafness and Other Communication Disorders (NIDCD) under the federal Research Related to Deafness and Communication Disorders program (CFDA 93.173), supports research into the neurological mechanisms underlying hearing loss. The central hypothesis is that the presentation of phosphatidylserine acts as a signal to mark inactive spiral ganglion neuron connections with outer hair cells for removal, facilitating...
- This Project Grant award of $659,102 from the National Institute on Deafness and Other Communication Disorders (NIDCD), under the "Research Related to Deafness and Communication Disorders" (CFDA 93.173) program, supports research on the functions and diseases of cochlear neurons. The research aims to: Identify molecular, proteomic, and functional markers of Type II auditory neurons and examine their functional roles using genetic tools. Determine the in vivo and in vitro functions of...
This three-year Project Grant from the National Science Foundation's Mathematical and Physical Sciences program, totaling $731,931, will fund research into the nonlinear dynamics of auditory hair cells and efferent neurons. Specifically, the University of California, Los Angeles will directly measure how stimulation of efferent neurons affects the sensitivity of hair cells to detect weak signals and withstand strong stimuli. Researchers will compare experimental findings to nonlinear dynamics models to explain how efference may provide dynamic feedback controlling hair cell sensitivity. This work aims to determine if efferent neurons constitute the feedback mechanism tuning hair cell nonlinear properties, exploring how efferent activity impacts mechanical responsiveness under different activity levels. Insights will complement prior in vivo and in vitro studies, as well as theoretical predictions of a self-tuning internal control parameter near a Hopf bifurcation. The project also includes mentoring opportunities through the Alliance for Graduate Education and the Professoriate Bridge Program.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $372.7k | 8/6/22 | ||
| Not listed | $179.6k | 6/28/22 | ||
| Not listed | $0 | 6/28/22 |