This Project Grant award, funded by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences Federal Grant Program (CFDA 47.049), supports research at the University of Texas at Austin to study how the secondary coordination sphere (SCS) affects the activity of copper enzymes. The $594,870 award from August 1, 2024 to July 31, 2027 employs a novel biosynthetic approach to modulate copper enzyme activity, with potential applications in areas like...
The University of Texas at Austin received a three-year, $450,000 Project Grant award from the National Science Foundation Division of Chemistry on September 15, 2021 to support research titled "SCAFFOLD-BASED BIOMIMETICS OF FE-HYDROGENASE AND NITROGENASE (FEMOCO): INTERROGATING DYNAMICS, PROTEIN MATRIX EFFECTS, AND CARBIDE MOTIFS." The award is part of NSF's Mathematical and Physical Sciences program (CFDA 47.049), which supports progress in these scientific fields to strengthen the...
The National Science Foundation (NSF) awarded a $463,709 Project Grant under the Mathematical and Physical Sciences (CFDA 47.049) program to the University of Texas at San Antonio (UTSA). This grant, awarded on April 1, 2025, supports a collaborative international research project led by Professors Oleg Larionov and Michael Doyle of UTSA, along with Professors Nicolas Blanchard and Jean-François Brière from France. The research aims to develop new catalytic methods to construct important...
The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $234,925 Project Grant to the University of Florida. The funding supports research conducted by Professor Kate Carroll to investigate post-translational protein cysteine modifications and the chemical reactivity of sulfur. The research explores how different cysteine thiol group modifications impact the properties of the sulfur atom, which is essential for understanding the role...
The National Science Foundation (NSF) Division of Chemistry awarded a $570,000 Project Grant to the University of Texas at Austin (UT Austin) under the Mathematical and Physical Sciences program (CFDA 47.049) to develop new supramolecular systems that exhibit stimulus-responsive changes in electronic structure, ion recognition, and self-assembly. The 3-year award, effective November 1, 2023, will support research by Professor Jonathan L. Sessler and coworkers to investigate the influence of...
The National Science Foundation (NSF) Division of Chemistry awarded a $500,000 Project Grant titled "TOPICS IN PROTEIN AND RNA FOLDING AND DYNAMICS" to the University of Texas at Austin under the Mathematical and Physical Sciences program (CFDA 47.049). This 4-year grant will support Professor Devarajan Thirumalai's research on the computational modeling of protein and RNA interactions and dynamics. Key focus areas include developing new methods to simulate intrinsically disordered...
The National Science Foundation Division of Chemistry awarded a $1,010,000 project grant to the University of Texas at Austin to develop innovative mass spectrometry methods for characterizing intact proteins through June 2025 under the Mathematical and Physical Sciences program (CFDA 47.049). Professor Jenny Brodbelt and her research group will apply ultraviolet photodissociation and other dynamic ion manipulation strategies to amplify structural and post-translational modification details...
This National Science Foundation (NSF) Project Grant award under the Mathematical and Physical Sciences program (CFDA 47.049) provides $343,638 to Texas A&M University-Commerce to conduct research on the thermochemistry, reaction dynamics, and conformational changes associated with the collisional activation of peptide ternary complexes and recombinant tagged proteins. The key products and services to be delivered through this 3-year grant include: Developing new zinc- and nickel-binding...
The University of Texas at San Antonio received a $483,119 Project Grant award from the National Science Foundation Division of Chemistry on August 1, 2021 to support catalytic cycloaddition reaction research and applications through July 31, 2024. The grant is part of NSF's Mathematical and Physical Sciences program (CFDA 47.049), which aims to advance scientific knowledge and understanding in these fields. Under the award, UTSA researchers will conduct work exploring catalytic cycloaddition...
This $550,000 Project Grant from the National Science Foundation Division of Chemistry, under the Mathematical and Physical Sciences program (CFDA 47.049), supports research at Texas A&M University from August 1, 2022 to July 31, 2025. Professor François Gabbaï and his team will investigate the synthesis and coordination chemistry of novel ambiphilic ligands featuring a carbenium ion positioned next to a phosphine- or carbene-based metal-binding site. When coordinated to late transition...