Project Grant 2204023
- This $208,879 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research between Marquette University and the Colorado School of Mines to gain molecular-level insights into the catalytic mechanism of nitrile hydratase enzymes. Professors Bennett, Fiedler, and Holz will employ kinetic, spectroscopic, biochemical, computational, and X-ray crystallographic methods to detect intermediates, test competing mechanistic...
- Under a $529,170 award from the National Science Foundation's (NSF) Mathematical and Physical Sciences (MPS) program (CFDA 47.049), Professor Robert Paton and his research team at Colorado State University (CSU) will develop new computational workflows to accelerate the discovery and optimization of highly selective catalysts. The project aims to advance mechanistic understanding and establish new quantitative descriptors for three key catalyst and ligand classes - hydrogen-bond donors,...
- With the support of a $258,403 Project Grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049), Carsten Milsmann of West Virginia University will study the electronic structures and reactivities of four-coordinate iron- and cobalt-carbene complexes as intermediates in carbene transfer catalysis. The research aims to develop design principles for using earth-abundant metal complexes to replace precious metal catalysts, with the potential to improve...
- This Project Grant award, valued at $450,000.00, was provided by the National Science Foundation (NSF) Division of Chemistry under the Mathematical and Physical Sciences (CFDA 47.049) Federal Grant Program. The award, effective from August 1, 2024 to July 31, 2027, supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University. The objective of this research program is to elucidate the fundamental mechanisms by which a...
- This $650,000 Project Grant awarded by the National Science Foundation's (NSF) Mathematical and Physical Sciences program (CFDA 47.049) funds an industrial-academic collaboration between Princeton University and the Merck Catalysis Laboratory. The goal is to develop new sustainable catalytic methods for the large-scale synthesis of pharmaceutical drugs using earth-abundant metals like iron, cobalt, and nickel instead of rare precious metals. The research aims to identify viable catalytic...
- This three-year, $180,149 project grant from the National Science Foundation's Mathematical and Physical Sciences program (CFDA 47.049) supports collaborative research on electrochemical nickel-catalyzed reductive biaryl coupling between researchers at the University of Wisconsin-Madison, University of Missouri-Kansas City, and Colorado State University. The team will use analytical, computational, and electroanalytical tools to study the mechanistic steps of these reactions and identify factors...
- This Project Grant from the National Science Foundation's Division of Chemistry provides $138,894 to Drs. Eranda Nikolla of Wayne State University and Will Medlin of the University of Colorado from January 2023 through December 2023. The funding supports research under the Mathematical and Physical Sciences program (CFDA 47.049) to develop an understanding of solid metal/metal oxide interfaces in inverted catalytic systems. Specifically, the researchers are synthesizing controlled metal...
- The National Science Foundation (NSF), through its Mathematical and Physical Sciences program (CFDA 47.049), awarded a $600,000 project grant to Professor Neil C. Tomson of the University of Pennsylvania. The 3-year project, starting on September 1, 2025, aims to study how iron-based catalysts can selectively activate and functionalize carbon-carbon sigma bonds under mild conditions. This research will lay the groundwork for future technologies that can produce pharmaceuticals, plastics, and...
- This $250,000 Project Grant award from the National Science Foundation (NSF) under the Mathematical and Physical Sciences (CFDA 47.049) program supports collaborative research to accelerate the discovery and design of dynamically evolving catalyst materials. The researchers will integrate advanced computer modeling, artificial intelligence, and machine learning with experimental methods to study how catalyst structures evolve during reactions, with the goal of developing more active, stable, and...
- This Project Grant award for $450,000 was provided by the National Science Foundation (NSF) through the Mathematical and Physical Sciences (CFDA 47.049) federal grant program. The funding supports collaborative research by Professors Yisong Guo of Carnegie Mellon University and Wei-Chen Chang of North Carolina State University to investigate a group of four enzymes that utilize a single iron atom and molecular oxygen to catalyze diverse chemical reactions. The goal is to elucidate the...
This $391,121 National Science Foundation project grant supports collaborative research between Marquette University and the Colorado School of Mines under the Mathematical and Physical Sciences program (CFDA 47.049). The three-year award will fund mechanistic studies of iron-type nitrile hydration catalysts through a combination of experimental and computational approaches. Researchers will employ kinetic, spectroscopic, biochemical, computational, and X-ray crystallographic methods to detect intermediates, test prevailing mechanistic hypotheses, and elucidate steps in metal active site maturation. Insights gained are expected to aid green catalytic approaches to hydrolytic reactions. In addition to advancing scientific understanding, the project provides graduate and undergraduate training and enhances research infrastructure at the awardee institutions.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $391.1k | 8/15/22 |