New York University received a $314,000 Project Grant award from the National Science Foundation Division of Chemical, Bioengineering, Environmental, and Transport Systems. The award is part of NSF's Engineering program (CFDA 47.041) and will fund research from July 1, 2021 to June 30, 2024 to bioengineer leukemic bone marrow niches and dissect heterogeneous mechanisms of leukemia chemo-resistance. The research aims to improve understanding of leukemia treatment failure through engineering models that simulate bone marrow microenvironments where chemotherapy drugs have difficulty reaching and eliminating all cancer cells. Findings could help identify new treatment targets and strategies to overcome resistance. The work will be performed in New York, NY by NYU researchers under the three-year award period.
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