Project Grant 20266701245558
- The University of Nebraska was awarded a $225,000 Project Grant from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program to conduct research aimed at improving the quality and development of in vitro produced (IVP) embryos for beef and dairy cattle. The goal is to understand how oxidative stress during oocyte culture impacts gene regulation and developmental competence of IVP embryos. The researchers will perform culture of oocytes under...
- This $650,000 Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program will support research on the role of interleukin-6 (IL6) family signaling proteins in early embryo and placental development in cattle. The 4-year project, running from Feb 1, 2026 to Jan 31, 2030, aims to: 1) Determine how IL6-family signals help an early embryo form properly, 2) Understand how...
- The Department of Agriculture's National Institute of Food and Agriculture awarded a $120,000 Project Grant under the Agriculture and Food Research Initiative competitive grants program to Virginia Polytechnic Institute & State University from July 2021 through June 2023. The grant funds research to investigate embryonic losses occurring during blastocyst hatching and embryo elongation in cattle, which can significantly impact the cattle industry. The principal investigator will...
- The federal Project Grant award of $650,000.00 from the USDA National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program supports research by Colorado State University to improve fertility and reproductive efficiency in the beef and dairy cattle industries. The project aims to activate the Nrf2 signaling pathway in bovine preimplantation embryos to mitigate oxidative stress and enhance embryo survival under suboptimal conditions,...
- This $650,000 Agriculture and Food Research Initiative (AFRI) Project Grant, awarded by the USDA National Institute of Food and Agriculture (CFDA 10.310), aims to improve the reproductive success of high-producing dairy cows. The research project has two main objectives: 1) understanding the nutritional needs of dairy cow embryos, particularly differences between lactating cows and younger heifers, in order to identify ways to better support embryo development; and 2) examining how oxygen and...
- This $500,000 project grant from the United States Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) supports research under the Agriculture and Food Research Initiative competitive federal grants program (AFRI; CFDA #10.310). The Virginia Polytechnic Institute and State University will characterize differences in early embryonic development and uterine environments between cattle breeds that are more resilient to undernutrition and less prone to pregnancy loss,...
- This is a Project Grant awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The $650,000 grant, awarded on February 1, 2026, will fund a 4-year research project at Purdue University to study how a special group of proteins called Trophoblast Kunitz Domain Proteins (TKDPs) produced by cattle embryos help them survive and form a healthy placenta during the crucial first...
- This $300,000 Project Grant awarded by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) aims to identify epigenetic modifications in the cattle placenta that are specifically from the sire or the dam, and determine how they influence gene expression during placental development. The overarching goal is to improve understanding of the complex biology of the placenta and how...
- This Project Grant award of $650,000.00 was provided by the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310). The grant supports research at Texas A&M AgriLife Research aimed at understanding the biological mechanisms underlying embryonic mortality in cattle. The central hypothesis to be investigated is that male and female genetics contribute differently to pregnancy...
- This $300,000 Project Grant from the USDA National Institute of Food and Agriculture (NIFA) Agriculture and Food Research Initiative (AFRI) program, awarded to Utah State University (USU) on July 1, 2024, aims to improve the efficiency of cattle cloning by studying the impact of increased polyadenylation (adding stabilizing tails to genetic messages) on egg quality and embryo development. The research hypothesis is that enhancing polyadenylation will lead to higher quality eggs, thereby...
This $225,000 federal Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Agriculture and Food Research Initiative (AFRI) CFDA 10.310 program supports research to improve in vitro embryo production (IVP) techniques for cattle. The project aims to determine if supplementing or inhibiting the action of "embryokines" - biological factors found in the uterus and embryo that are essential for embryo development and pregnancy success - can improve IVP embryo quality and subsequent embryo development in cattle. This research will serve two purposes: 1) evaluating if supplementing embryokines improves IVP embryo quality and pregnancy rates, and 2) identifying the essential embryokines for proper embryo formation and pregnancy establishment in cattle. The project will use both laboratory approaches and applied cattle studies, including supplementing IVP embryos with certain embryokines or using CRISPR gene editing to inhibit embryokine function. This work aims to enhance IVP techniques and improve sustainability in the cattle industry to meet the growing global demand for protein and milk.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $225.0k | 11/19/25 |