Project Grant 20247704543081
- The University of Minnesota, Office of Sponsored Projects Administration, received a $1.34M Cooperative Agreement award from the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), effective February 2, 2026, through February 1, 2029. The project addresses critical gaps in understanding highly pathogenic avian influenza (HPAI) susceptibility and transmission in turkeys,...
- Federal Project Grant Award Summary Purdue University received a $449,020 Project Grant from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Laying Hen and Turkey Research Program (CFDA 10.245), awarded September 15, 2025, with a completion date of September 14, 2028. The project will investigate the mechanisms by which subtherapeutic antibiotics promote animal growth, with particular focus on the role of commensal gut microbiota in this...
- Summary Louisiana State University will develop novel mucosal vaccines to protect poultry from Highly Pathogenic Avian Influenza (HPAI) H5N1 Clade 2.3.4.4b under a $1.92 million Cooperative Agreement awarded by the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025). The project, which commenced February 2, 2026, and concludes February 1, 2029, will deliver three primary...
- Federal Cooperative Agreement Summary Colorado State University's Sponsored Programs Division received a $2,015,677 cooperative agreement from the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), awarded February 2, 2026, with completion targeted for February 1, 2029. The award funds the development of a novel probiotic-based vaccine to protect poultry from highly...
- This Project Grant from the Department of Agriculture's National Institute of Food and Agriculture, under the Small Business Innovation Research (SBIR) Program/Small Business Technology Transfer (STTR) Program (CFDA 10.212), provides $135,484 to Larad Inc. to develop an enzyme-linked immunosorbent assay (ELISA) kit. The kit aims to differentiate between Marek's disease virus infected and herpesvirus of turkeys vectored vaccinated poultry flocks. Larad will purify individual glycoprotein antigens...
- Summary The Animal and Plant Health Inspection Service (APHIS) awarded the Regents of the University of Minnesota a Cooperative Agreement valued at $810,568 under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), effective February 2, 2026, through February 1, 2029. The primary deliverable is development and efficacy assessment of a novel lactococcal-phage vaccine designed to protect poultry from highly pathogenic avian influenza (HPAI) H5N1 Clade 2.3.4.4b. The...
- Grant Award Summary The University of Florida's Division of Sponsored Research received a $650,000 Project Grant from the USDA National Institute of Food and Agriculture under the Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310), effective from September 15, 2025, through September 14, 2028. This three-year research initiative focuses on developing and optimizing Self-Destructing Attenuated Adjuvant Salmonella (SDAAS) strains as immunological delivery vehicles for commercial...
- Federal Cooperative Agreement Summary Texas A&M AgriLife Research received a $871,330 Cooperative Agreement from the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), effective February 2, 2026, with completion targeted for February 1, 2029. The primary deliverable is the development of novel Marek's Disease Virus (MDV) vector vaccines designed to protect poultry against...
- Federal Cooperative Agreement Summary The University of Georgia Research Foundation, Inc. received a $1,999,873 Cooperative Agreement from the U.S. Department of Agriculture's Animal and Plant Health Inspection Service (APHIS) under the Plant and Animal Disease, Pest Control, and Animal Care program (CFDA 10.025), awarded February 2, 2026, with completion targeted for February 1, 2029. The project addresses the urgent threat of highly pathogenic avian influenza (HPAI) to the U.S. poultry...
- This Project Grant award of $649,943.00 from the U.S. Department of Agriculture's (USDA) Agriculture and Food Research Initiative (AFRI) program (CFDA 10.310) supports the development and updating of vaccines against influenza A virus of swine. The University of Nebraska is the primary awardee and will leverage its multidisciplinary expertise in agricultural research, technology innovation, and vaccine development to deliver this versatile, non-infectious vaccine platform. The project aims to...
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** CLOSTRIDIAL DERMATITIS (CD), ALSO KNOWN AS GANGRENOUS DERMATITIS (GD), IS A MAJOR PROBLEM FOR THE TURKEY INDUSTRY IN THE UNITED STATES, CAUSING SIGNIFICANT FINANCIAL LOSSES. THIS DISEASE IS MAINLY CAUSED BY TWO BACTERIA: C. SEPTICUM AND C. PERFRINGENS. C. SEPTICUM CAN CAUSE HIGH DEATH RATES IN TURKEYS, WHILE C. PERFRINGENS NOT ONLY CAUSES CD BUT ALSO LEADS TO A DEADLY INTESTINAL DISEASE CALLED NECROTIC ENTERITIS (NE), WHICH COSTS THE POULTRY INDUSTRY $6 BILLION ANNUALLY. ALTHOUGH WE DEVELOPED THE FIRST VACCINE TARGETING C. PERFRINGENS-INDUCED NE IN 2020, THERE IS STILL NO EFFECTIVE WAY TO CONTROL C. SEPTICUM. TO SOLVE THE PROBLEM OF CD, WE NEED TO TARGET BOTH BACTERIA. THIS PROJECT AIMS TO HELP NOT ONLY THE TURKEY AND LAYER INDUSTRY BUT ALSO THE ENTIRE POULTRY INDUSTRY.WE WILL USE INNOVATIVE TECHNIQUES TO TACKLE C. SEPTICUM. OUR LICENSED VACCINE CONTAINS TWO COMPONENTS THAT TARGET C. PERFRINGENS. WE HAVE ALSO FOUND ONE COMPONENT THAT PROTECTS AGAINST BOTH C. PERFRINGENS AND C. SEPTICUM, AND TWO ADDITIONAL COMPONENTS THAT TARGET C. SEPTICUM. WE WILL USE THESE FIVE COMPONENTS TO DEVELOP NEW VACCINES THAT TARGET BOTH BACTERIA. THESE VACCINES WILL BE DELIVERED ORALLY OR THROUGH A SPRAY USING A HARMLESS FORM OF SALMONELLA TO PROTECT TURKEYS AND LAYERS FROM CD AND NE. THIS PROJECT WILL BENEFIT TURKEY AND LAYER FARMERS BY IMPROVING THE EFFICIENCY AND SUSTAINABILITY OF POULTRY PRODUCTION. IT WILL ALSO PROVIDE VALUABLE DATA THAT COULD HELP PROTECT AGAINST OTHER DISEASES NOT COVERED BY THIS PROJECT. ADDITIONALLY, THE VACCINE MAY REDUCE THE SPREAD OF SALMONELLA, IMPROVING FOOD SAFETY. BY PREVENTING CD AND NE, WE CAN SIGNIFICANTLY REDUCE THE NEED FOR ANTIBIOTICS IN AGRICULTURE. THIS REDUCTION IN ANTIBIOTIC USE HELPS TO PREVENT THE DEVELOPMENT AND SPREAD OF ANTIBIOTIC-RESISTANT BACTERIA, WHICH IS A MAJOR CONCERN FOR BOTH ANIMAL AND HUMAN HEALTH. THIS ALIGNS WITH USDA GOALS TO SUPPORT A PROSPEROUS AGRICULTURAL SYSTEM AND PROVIDE SAFE, NUTRITIOUS FOOD. THE PROJECT IS IMPORTANT FOR THE ECONOMY, COMMUNITY, ENVIRONMENT, AND OVERALL AGRICULTURAL HEALTH.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $462.5k | 6/26/24 |