This three-year, $630,000 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture (USDA NIFA) supports research under the Agriculture and Food Research Initiative (AFRI) federal grant program. The grant funds a study at Michigan State University investigating the role of histamine in causing increased gut permeability and inflammation in weaned pigs. Early weaning is stressful for piglets and can result in long-term inefficiencies. The project will examine histamine, which is released by immune cells in response to stress, as a potential target for mitigating leaky gut and inflammation post-weaning. Controlling histamine levels may provide a novel strategy to optimize pig health and growth performance. The research aims to establish histamine as a cause of weaning-related gut issues in pigs. Findings could inform future management practices focused on histamine to improve pig welfare and profitability in the pork industry.
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