Project Grant 20226701436288
- This National Science Foundation Project Grant of $659,112 will fund research at Dickinson College from June 2022 to May 2025 under the Biological Sciences program (CFDA 47.074). The research aims to investigate sulforaphane, a compound found in cruciferous plants like broccoli and cauliflower, as a potential "epigenetic weapon" against destructive insect pests through its ability to inhibit histone deacetylases in insect larvae. Specifically, the project will examine the impacts of...
- The University of Maryland, College Park will receive $499,961 from the US Department of Agriculture National Institute of Food and Agriculture under the Biotechnology Risk Assessment Research program to conduct genomic monitoring of insect pest populations for emerging resistance to pest management technologies from August 1, 2022 to July 31, 2025. The project aims to assess the strengths and limitations of genomic monitoring approaches for detecting emerging resistance in different pest...
- Lepidext, Inc. was awarded a $100,000 Project Grant from the United States Department of Agriculture National Institute of Food and Agriculture under the Small Business Innovation Research (SBIR) Program / Small Business Technology Transfer (STTR) Program (CFDA 10.212) to further develop an agent with potential to actively suppress populations of Bacillus thuringiensis (Bt) resistant pest insects. The SBIR/STTR programs support scientific excellence and technological innovation through federal...
- This Project Grant awarded by the National Science Foundation (CFDA 47.074 - Biological Sciences) to the University of Georgia Research Foundation provides $509,821 in funding from July 1, 2025 to June 30, 2028 to investigate the ecological-evolutionary dynamics between the pea aphid and its parasitoid wasp, Aphidius ervi. The project aims to uncover how the balance between resistant and susceptible pea aphids is maintained, and how agricultural management practices can reduce the risks of...
- This $687,357 Project Grant award from the National Science Foundation's Biological Sciences program (CFDA 47.074) supports research to study repeated evolution in a diverse group of alpine beetles. The researchers will explore whether natural selection has acted on the same molecular pathways as species adapted to alpine environments during past climate cycles. Comparative genomic and stress tolerance experiments will test for evidence of repeated evolution and identify the genetic mechanisms...
- The Department of Agriculture National Institute of Food and Agriculture awarded a $164,954.99 Project Grant through the Agriculture and Food Research Initiative (AFRI) program to the University of Maryland, College Park. The grant aims to identify novel insecticidal targets that disrupt the insect ecdysis (molting) process, with a focus on the role of acetylcholine signaling in regulating pupal ecdysis across major agricultural pest orders. The project will employ multiple agonists and...
- This $3,996,373 Project Grant award from the U.S. Department of Agriculture's National Institute of Food and Agriculture (NIFA) under the Specialty Crop Research Initiative (CFDA 10.309) aims to create resilient integrated pest management (IPM) programs for eastern tree fruit enterprises. The award recipient, the Agricultural Research Service (ARS) Northeast Area, will lead a transdisciplinary team of researchers and extension specialists in entomology, horticulture, economics, and social...
- This Project Grant award of $763,751 from the National Science Foundation's (NSF) Biological Sciences program (CFDA 47.074) will fund research by Tufts University to investigate the speciation process and barriers to gene exchange in the European corn borer moth. The key research objectives are to: 1) explore the history of species spread and potential co-occurrence of distinct barriers through genome resequencing, 2) determine if prezygotic isolation traits contribute to postzygotic isolation...
- This $844,511 Project Grant was awarded by the National Science Foundation (NSF) Biological Sciences Program (CFDA 47.074) to the University of Wisconsin-Madison to investigate the ecological-evolutionary dynamics of pea aphids and their parasitoid wasp predator Aphidius ervi. The research aims to understand how the rapid evolution of the agricultural pest pea aphid, which can develop resistance to its natural predators, impacts the maintenance of biodiversity and the ability to control pests...
- This award from the National Science Foundation's Biological Sciences program, CFDA 47.074, provides $1,335,651 to The University Of Kentucky Research Foundation to conduct research on speciation with gene flow in a pair of pine-feeding insect species. The project aims to understand how some species can maintain genetic differences despite ongoing gene exchange. Key research activities include: Larval diet manipulations and transcriptome analyses to quantify reproductive isolation and...
** AWARDS ISSUED PRIOR TO JANUARY 20, 2025, WERE FUNDED UNDER PREVIOUS ADMINISTRATIONS AND MAY NOT REFLECT THE PRIORITIES AND POLICIES OF THE CURRENT ADMINISTRATION.** AGRICULTURAL INSECT PESTS SHOW A REMARKABLE ABILITY TO EVOLVE RESISTANCE TO INSECTICIDES. ALTHOUGH INSECTICIDE RESISTANCE IS WIDELY CONSIDERED TO BE INEVITABLE, THE EVOLUTIONARY PROCESSES UNDERLYING THE EVOLUTION OF INSECTICIDE RESISTANCE REMAIN POORLY UNDERSTOOD. ONE POSSIBLE EXPLANATION IS THAT INSECTICIDE EXPOSURE MAY ALTER EPIGENETIC MODIFICATIONS, WHICH ALTER HERITABLE PATTERNS OF GENE EXPRESSION WITHOUT ACTUALLY CHANGING THE UNDERLYING DNA SEQUENCE. ENVIRONMENTAL STRESS HAS BEEN SHOWN TO INFLUENCE GENOME-WIDE PATTERNS OF DNA METHYLATION (A METHYL GROUP ADDED CPG DINUCLEOTIDE), ALTERING PATTERNS OF GENE EXPRESSION.THE COLORADO POTATO BEETLE (CPB), LEPTINOTARSA DECEMLINEATA, HAS BEEN EXTRAORDINARILY SUCCESSFUL AT ADAPTING TO ALL INSECTICIDES CLASSES, INCLUDING THE NEONICOTINOID INSECTICIDE IMIDACLOPRID. WE WILL USE AN EXPERIMENTAL EVOLUTION APPROACH TO TEST HOW BEETLE EXPOSURE TO SUBLETHAL DOSES OF IMIDACLOPRID CAN ALTER MULTIGENERATIONAL AND TRANSGENERATIONAL EPIGENETIC INHERITANCE OF INSECTICIDE TOLERANCE.
Mod # | Description | ReasonForModification | Federal Obligation | Date |
|---|---|---|---|---|
| Not listed | $683.5k | 12/6/21 |