A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS
Added: Aug 05, 2011 1:17 pm
1. National Institutes of Health, Bethesda, MD 20892 and Centers for Disease Control and Prevention, Atlanta, GA 30305 are soliciting proposals from small business concerns that possess the research and development (R&D) expertise to conduct innovative research that will contribute toward meeting the program objectives of the agencies. A SOLICITATION OF THE NATIONAL INSTITUTES OF HEALTH (NIH) AND THE CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) FOR SMALL BUSINESS INNOVATION RESEARCH (SBIR) CONTRACT PROPOSALS [PHS 2012-1], with a closing date of November 7, 2011, for receipt of proposals, soon will be available electronically through the NIH Small Business Research Funding Opportunities (http://grants.nih.gov/grants/funding/sbir.htm) Web site. The SBIR Phase I Contract Solicitation will be available ONLY via electronic means. Printed copies of the Solicitation will not be distributed. Potential offerors are encouraged to check the NIH Small Business Research Funding Opportunities Web site for updates on the program. Any updates or corrections to the Solicitation will be posted there. The purposes of the SBIR program are to: (a) stimulate technological innovation in the private sector; (b) strengthen the role of small business in meeting Federal research/research & development (R/R&D) needs; (c) increase the commercial application of Federally-supported research results; (d) foster and encourage participation by socially and economically disadvantaged small business concerns and women-owned business concerns; and improve the return on investment from Federally-funded research for economic and social benefits to the Nation. For purposes of the SBIR program, a small business concern is any business concern that, on the date of award, (1) is organized for profit, with a place of business located in the United States, which operates primarily within the United States or which makes a significant contribution to the United States economy through payment of taxes or use of American products, materials or labor; (2) is in the legal form of an individual proprietorship, partnership, limited liability company, corporation, joint venture, association, trust or cooperative, except that where the form is a joint venture, there can be no more than 49 percent participation by foreign business entities in the joint venture; (3) is at least 51 percent owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States; or is owned and controlled by another (one) small business concern that is itself at least 51 percent owned and controlled by one or more individuals who are citizens of, or permanent resident aliens in, the United States; AND (4) has, including its affiliates, no more than 500 employees. Following are the research topics identified in the NIH/CDC SBIR Contract Solicitation [PHS 2012-1]: NATIONAL INSTITUTES OF HEALTH (NIH) – NATIONAL CANCER INSTITUTE (NCI): Development of Anticancer Agents; Development of Companion Diagnostics; Development of Radiation Modulators For Use During Radiotherapy; Reformulation of Cancer Therapeutics using Nanotechnology; Probing Tumor Microenvironment Using In Vivo Nanotechnology-based Sensors; Development of Innovative Algorithms for Processing & Analysis of In Vivo Images; Novel Imaging Agents to Expand the Clinical Toolkit for Cancer Diagnosis, Staging, and Treatment; Automated Collection, Storage, Analysis, and Reporting Systems for Dietary Images; Development of Low Cost, Small Sample Multi-Analyte Technologies for Cancer Diagnosis, Prognosis and Early Detection; Simplified Tissue Microarray Instrument For Clinical and Research Settings (NIH Technology Transfer); High Throughput Isolation of Antigen Specific T-cells for Cancer Therapy (NIH Technology Transfer); Generation and Qualification of Site-specific Post-translationally Modified Proteins for Use as Calibrators in Pharmacodynamic (PD) Assays. NATIONAL CENTER FOR RESEARCH RESOURCES (NCRR): Development of an Integrated Automated High Throughput Platform for Large-Scale Genetic and Therapeutic Screening in Zebrafish. NATIONAL HEART, LUNG AND BLOOD INSTITUTE (NHLBI): Development of Induced Pluripotent Stem (iPS) Cell Lines for Use in Cell-based Bioassays; Novel Technologies for Powering Ventricular Assist Devices; Reagents for Studying Human Lung Cell Biology and Cellular Function; Novel Technologies for Assessing Lipoprotein Sub-fractions; Computer Generated Diet and Exercise Reminders Promoting Cardiovascular Health; Haptoglobin Treatment to Reduce Complications of Sickle Cell Disease; Transmit-receive Surface Array Coils for MRI of Patients with Internal Conductive Devices; Multilayer-coated Gratings for Phase-Contrast Computed Tomography; Wireless Physiologic Telemetry for Interventional MRI; Bioabsorbable Stents for Pediatric Pulmonary Artery Stenosis and Aortic Coarctation; Electrophysiologic Catheters for Interventional MRI Ablation of Ventricular Tachycardia. NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM (NIAAA): Discovery and Preclinical Development of Novel Compounds to Treat Alcohol Use Disorders. NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES (NIDDK): A Low Molecular Weight Thyroid-Stimulating Hormone Receptor Agonist for Thyroid Cancer (NIH TT). NATIONAL INSTITUTE ON DRUG ABUSE (NIDA): Confirming Compliance with Experimental Pharmacotherapy Treatment of Drug Abuse; Development of a Solid Oral Dosage Form for Fenobam; Recovery Warrior: Behavioral Activation Video Game for Substance Abuse via a Commercially Available Active & Interactive Gaming Platform (e.g., Wii, Play Station Move, or Xbox Kinect); Highly Effective Methods for Systemic In Vivo Targeted Delivery of shRNAi to the Brain for Treatment of Substance Use Disorders and Other Brain Disorders; Feasibility of Development of RNAi-based Therapeutics for Treatment of HIV and HCV Infections in Drug Abusing Populations; Smokescreen: Genetic Screening Tool for Tobacco Dependence and Treatment Approaches; Feedback-regulated Naloxone Delivery Device to Prevent Opiate Overdose Deaths; Drugged Driving: Future Research Directions. CENTERS FOR DISEASE CONTROL AND PREVENTION (CDC) – CENTER FOR GLOBAL HEALTH (GCH): The Development of Lateral Flow Immunochromatographic Devices to Detect Antibodies; Development of a Blood Donor Screening Test to Prevent Transfusion Transmitted Babesiosis. NATIONAL CENTER ON BIRTH DEFECTS AND DEVELOPMENTAL DISABILITIES (NCBDDD): Development of an Assay to Rapidly Determine Folate Insufficiency in the Field. NATIONAL CENTER FOR EMERGING ZOONOTIC AND INFECTIOUS DISEASES (NCEZID): Vaccine Adverse Event Reporting System (VAERS) Application for Smartphone; Development of Rapid, Point-of-Care Tests for Diagnosis of Fungal Infections. NATIONAL CENTER FOR HIV/AIDs, VIRAL HEPATITIS, STD, AND TB PREVENTION (NCHHSTP): Testing the Efficacy of HIV Prevention Strategies in Nonhuman Primate Models; Data Mining Software for Large-Scale Analyses of Infections Caused by Hepatitis Viruses; Developing a Location-Based Application to Identify Adolescent-Friendly Health Care Services. OFFICE OF PUBLIC HEALTH PREPAREDNESSA ND RESPONSE (OPHPR): Emergency Vehicle Proximity Alert System.2. NIH/CDC SBIR Contract Solicitation PHS 2012-1, including proposal forms, will be available electronically on/around August 24, 2011 through the NIH Small Business Research Funding Opportunities Web site. (Note: The PHS 2011-2 Omnibus Solicitation of the National Institutes of Health, Centers for Disease Control and Prevention, Food and Drug Administration, and Administration for Children and Families for Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) GRANT Applications, where investigator-initiated ideas are encouraged, is still open and is available at the same Web site noted above with a remaining due date of December 5, 2011.) To understand better the differences between grants and contracts, see Contracts vs. Grants: What's the difference? (http://grants.nih.gov/grants/funding/contracts_vs_grants.htm) LINKURL: http://grants.nih.gov/grants/funding/sbir.htm LINKDESC: National Institutes of Health Small Business (SBIR/STTR) Research Funding Opportunities. E-mail: sbir@od.nih.gov
PHS-2012-1 Department of Health and Human Services National Institutes of Health
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