This is a Small Business Innovation Research (SBIR) Phase I contract awarded by the National Institutes of Health (NIH), part of the Department of Health and Human Services (HHS), to Luna Innovations Incorporated. The objective of this $299,956 Firm Fixed Price contract is to develop a novel layer-by-layer (LBL) RNA vaccine that can provide long-lasting protection against HIV. Luna Innovations is a small business that specializes in fiber optic sensing and measurement systems, and has previously...
This is a $299,999.00 Firm Fixed Price Definitive Contract awarded by the Department of Health and Human Services National Institutes of Health National Institute of Allergy and Infectious Diseases to Luna Innovations Incorporated, a small business manufacturer, for the CNT-VECTORED DELIVERY OF MRNA FOR HIV-VACCINES research project under the Small Business Innovation Research (SBIR) Program Phase I. The contract is for the development and delivery of products and services related to this...
This is a $300,000.00 Small Business Innovation Research (SBIR) Program Phase I contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID) to Luna Labs USA LLC, a small business manufacturer based in Charlottesville, Virginia. The contract is for the development of a rapid nucleic acid test for HIV-1, with a period of performance through April 2025. The contract includes two subcontractors - Gener8, LLC, a medical device manufacturer providing engineering services...
This is a $600,000.00 Firm Fixed Price contract awarded by the National Institutes of Health (NIH), part of the Department of Health and Human Services (HHS), to Nanocomposix, Inc., a small business manufacturer of engineered nanoparticles. The objective is to develop an effective human immunodeficiency virus (HIV) vaccine using engineered nanoparticles loaded with messenger RNA (mRNA) targeted to antigen presenting cells. This contract is part of the Small Business Innovation Research (SBIR)...
This is a $599,999 Firm Fixed Price contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. Department of Health and Human Services, to Parabon NanoLabs, Inc., a small business. The objective of the contract is to develop a DNA-based HIV vaccine that will stimulate production of broadly neutralizing antibodies against the HIV-1 envelope protein trimer antigen. This is a Phase I Small Business Innovation Research (SBIR) contract under the...
The National Institute of Allergy and Infectious Diseases (NIAID), a civilian agency within the Department of Health and Human Services, has awarded a $3,782,538.00 Delivery Order contract to Advanced Bioscience Laboratories, Inc. (ABL) to support the feasibility assessment for the development of a liposome/lipid nanoparticle (LNP) displaying an HIV envelope trimer protein and containing/incorporating messenger RNA (mRNA). This contract is part of NIAID's broader Preclinical And Translational...
This is a $599,914 firm-fixed-price contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the U.S. Department of Health and Human Services, to Antagen Biosciences Inc. (doing business as Antagen Pharmaceuticals), a small disadvantaged and minority-owned biotechnology company. The objective of this SBIR Phase I research contract is to develop a nanoparticle-based vaccine delivery platform to induce broadly neutralizing antibodies against HIV. The work will...
This is a Small Business Innovation Research (SBIR) contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), to Luna Labs USA LLC, a subsidiary of Luna Innovations Incorporated. The $599,993.00 firm fixed-price contract is for developing "Reagents for Immunologic Analysis of Non-Mammalian and Underrepresented Mammalian Models." This SBIR contract is set aside for small businesses and supports NIAID's mission...
This federal contract award, with a total ceiling value of $2,250,744.00, was issued by the National Institute of Allergy and Infectious Diseases (NIAID) to the International AIDS Vaccine Initiative (IAVI), a global non-profit organization focused on HIV vaccine development. The purpose of the contract is to develop an optimized Phase 1 current Good Manufacturing Practice (cGMP) manufacturing process for lipid nanoparticle (LNP) fabrication that enables covalent coupling of an HIV-1 envelope...
The U.S. National Institute of Allergy and Infectious Diseases (NIAID) awarded a Small Business Innovation Research (SBIR) Phase I contract to Luna Innovations Incorporated, a leading provider of advanced fiber optic sensing and measurement systems. The contract, valued at $224,997, is for the development of "INNOVATIVE ORAL FORMULATIONS FOR ANTI-TB DRUGS." This Firm Fixed Price contract has an ultimate completion date of August 25, 2017. Luna Innovations, a for-profit manufacturer, is...
This is a Small Business Innovation Research (SBIR) Phase II contract awarded by the National Institute of Allergy and Infectious Diseases (NIAID), a component of the National Institutes of Health (NIH), to Luna Labs USA LLC, a subsidiary of Luna Innovations Incorporated, for the development of a platform for the delivery of mRNA-based HIV vaccines.
The $1,999,997.00 Firm-Fixed-Price contract involves collaborating with New York University (NYU) to evaluate the immunogenicity of novel HIV vaccine immunogens. NYU will produce and characterize the proteins, which will then be co-delivered with the mRNA constructs formulated by Luna Labs using their carbon nanotube (CNT) delivery platform. The goal is to down-select the best performing CNT-mRNA formulation for further testing in rabbit studies.
This contract is part of NIAID's efforts to support the development of innovative HIV vaccine technologies through the SBIR program, which provides funding to small businesses for the research and development of promising technologies.