This is a $1,280,770 cooperative agreement awarded by the National Aeronautics and Space Administration (NASA) Shared Services Center to the National Council On Radiation Protection & Measurements (NCRP), a non-profit organization based in Bethesda, MD. The purpose of the contract is to determine whether sex differences exist for radiation-induced lung cancers across exposed populations, address the issues of transferring radiation risk data from the Japanese atomic bomb survivors to the...
This is a $7,516,772.62 cooperative agreement awarded by the Shared Services Center, a civilian federal agency, to the National Council On Radiation Protection & Measurements, a non-profit organization based in Bethesda, Maryland. The contract is for an epidemiologic study on neurobehavioral, depression, cognitive impairment, and other adverse conditions in submariners related to the interaction between radiation and multiple other stressors, to support risk assessment for astronauts. The...
This is a three-year grant awarded by the National Aeronautics and Space Administration (NASA) to the National Council on Radiation Protection and Measurements (NCRP), a non-profit organization based in Bethesda, Maryland. The grant is for an in-depth study to more fully understand the risk of central nervous system (CNS) effects following radiation exposures in space and to provide guidance for risk management and radiation protection.
The grant is a follow-on to a previous Phase 1 effort...
The National Aeronautics and Space Administration (NASA) has awarded a $2,476,960.00 grant to Brigham & Women's Hospital Inc., a not-for-profit hospital and research institution in Boston, Massachusetts. The grant is for a research project aimed at understanding the short- and long-term effects of space radiation on cognition, motor abilities, fatigue, anxiety, and changes in the brain and cardiovascular system. The project will use animal models, including Alzheimer's disease transgenic...
This is a $277,796.43 doctoral research project awarded by the Shared Services Center, a civilian federal agency, to the Regents of the University of Colorado (CU). The contract is focused on developing a framework and model to evaluate the mortality risk and performance degradation of astronaut crew members due to space radiation and other spaceflight stressors like microgravity. This work aims to address NASA's need for tools to reduce uncertainty in radiation effects on human health and...
This is a $1,876,306.00 grant award from NASA to Eastern Virginia Medical School (EVMS) to conduct a research study on the impact of hadron radiation exposure on brain function and neurocognition for astronauts on deep space missions. The study aims to determine the severity of impairments in executive function performance, changes in neurotransmitter release, and effects on sleep and recovery after exposure to high energy protons, oxygen, and silicon particles. The research will address key...
This is a $2,121,119 grant awarded by NASA to the Old Dominion University Research Foundation (ODURF) to conduct research on the effects of high-energy particle radiation (HZE particles) on neurocognitive functions in astronauts during deep space missions. The goal is to determine the threshold dose of exposure for spatial memory impairment (HISMI) and attentional set-shifting impairment (HIASSI), as well as identify changes in the brain proteome associated with susceptibility or resistance...
The National Aeronautics and Space Administration (NASA) awarded a $2,399,359.00 grant for research to Emory University, a private research university located in Atlanta, Georgia. The grant is focused on improving the understanding of the mechanisms underlying the high relative biological effectiveness (RBE) of galactic cosmic radiation (GCR) for carcinogenesis, including its ability to elicit non-targeted effects. The research aims to investigate the role of the NAD+/PARP1/sirtuin axis in...
This is a delivery order awarded by the Headquarters agency to the National Academy of Sciences (NAS), a private non-profit organization, to provide an assessment of options for managing cancer risks associated with radiation exposure following crewed space missions. The contract, valued at $700,000, has an ultimate completion date of September 1, 2021. NAS frequently receives federal contracts and grants to provide research, analysis, and advisory services across various domains, including...
This $9,007,528.58 federal grant award by the National Aeronautics and Space Administration (NASA) to the University of California, Irvine (UC Irvine) is focused on resolving the mechanisms leading to radiation-induced cognitive dysfunction in humans exposed to the space radiation environment. The research aims to improve risk estimates for early and late central nervous system (CNS) effects caused by this exposure. The grant involves a comprehensive series of mechanistic studies analyzing...